I had put together a birthday card illustration piece for a good friend last year, and she loved the concept so much that I was commissioned to do a full illustration that she plans to get tattooed. Very cool, and very flattering. :-)
The original was done with a micron pen, pretty sure there was some graphite sketch work that was done beforehand to get the composition down. The final color piece was done digitally using my wacom intuos 3 tablet. The print came out fairly decent, but I am still on the hunt for a good print shop to work with...
Here is the final:
Here is the original birthday card: